Thermo Fisher Scientific HCK Monoclonal Antibody (2A6)
인간 HCK 단백질을 인식하는 마우스 단클론 항체로, Western blot, ELISA, in situ PLA에 사용 가능. Affinity chromatography로 정제된 액상 항체이며, PBS(pH 7.4) 버퍼에 보존제 없이 제공. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 3 ng/mL |
| in situ PLA | 1:1200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2A6 |
| Immunogen | HCK (AAH14435, 1 a.a. ~ 80 a.a) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MGCMKSKFLQ VGGNTFSKTE TSASPHCPVY VPDPTSTIKP GPNSHNSNTP GIREAGSEDI IVVALYDYEA IHHEDLSFQK
Target Information
Hematopoietic cell kinase (HCK) is a SRC-related kinase expressed in lymphoid and hematopoietic cells and may play a role in certain forms of leukemia.
HCK (Alias: DKFZp686D0638) is a protein-tyrosine kinase predominantly expressed in hemopoietic cell types. It may couple the Fc receptor to activation of the respiratory burst and play a role in neutrophil migration and degranulation.
Alternate translation initiation site usage, including a non-AUG (CUG) codon, results in two isoforms with different subcellular localization.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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