Thermo Fisher Scientific SIRT7 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

2 µg/mL

-

Immunocytochemistry (ICC/IF)

1:20-1:100

-

Immunoprecipitation (IP)

Assay-dependent

-

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide corresponding to residues 100-200 of an internal portion of human SIRT7. [Swiss-Prot# Q9NRC8] if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SIRT7,uniProtId:Q9NRC8-1,ncbiNodeId:9606,antigenRange:100-200,antigenLength:400,antigenImageFileName:PA1-46468_SIRT7_Q9NRC8-1_Rabbit.svg,antigenImageFileNamePDP:PA1-46468_SIRT7_Q9NRC8-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Storage conditions

4° C, do not freeze

Shipping conditions

Wet ice

RRID

AB_1960655

Product Specific Information

The target sequence has 88% sequence homology with bovine and porcine and 82% sequence homology with drosophila.

Suggested positive control: antigen standard for SIRT7 (transient overexpression lysate), human liver protein.

Target Information

SIRT7 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. SIRT7 is included in class IV. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. SIRT7 is included in class IV of the sirtuin family.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.