Thermo Fisher Scientific SIRT7 Polyclonal Antibody
SIRT7 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot, ICC/IF, IP에 사용 가능. 인간 SIRT7의 내부 서열(100-200 aa)에 대한 합성 펩타이드로 제작. 1 mg/mL 농도의 액상 형태로 제공되며, 4°C 보관. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 2 µg/mL | |
| Immunocytochemistry (ICC/IF) | 1:20–1:100 | |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues 100–200 of an internal portion of human SIRT7 (Swiss-Prot# Q9NRC8) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Wet ice |
| RRID | AB_1960655 |
Product Specific Information
- The target sequence shows 88% sequence homology with bovine and porcine, and 82% with Drosophila.
- Suggested positive control: antigen standard for SIRT7 (transient overexpression lysate), human liver protein.
Target Information
SIRT7 is a member of the sirtuin family of proteins, homologous to the yeast Sir2 protein. Members of this family possess a conserved sirtuin core domain and are grouped into four classes, with SIRT7 belonging to class IV. Although the functions of human sirtuins are not fully determined, yeast sirtuins are known to regulate epigenetic gene silencing and suppress rDNA recombination. Studies suggest that human sirtuins may act as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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