Thermo Fisher Scientific RANBP1 Monoclonal Antibody (OTI8E1), TrueMAB
RANBP1 단백질을 인식하는 마우스 단클론 항체로 Western blot에 적합. Human, Mouse, Rat 반응성. Lyophilized 형태로 공급되며 1 mg/mL 농도. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8E1 |
| Immunogen | Full length human recombinant protein of human RANBP1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Ran/TC4-binding protein (RanBP1) interacts specifically with GTP-charged RAN.
RANBP1 encodes a 23-kDa protein that binds RAN complexed with GTP but not GDP.
It does not activate GTPase activity of RAN but enhances GTP hydrolysis by RanGAP1.
RANBP1 cDNA encodes a 201-amino acid protein, 92% similar to its mouse homolog.
In mammalian and yeast cells, RanBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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