Thermo Fisher Scientific GCKR Monoclonal Antibody (OTI1E7), TrueMAB
Human GCKR 단백질을 인식하는 마우스 모노클로날 항체로, Western blot, IHC, ICC/IF 등에 적합. TrueMAB 형식으로 고순도 정제된 액상 제품이며, 연구용으로만 사용 가능. -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E7 |
| Immunogen | Full length human recombinant protein of human GCKR produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins.
The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme.
This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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