Thermo Fisher Scientific WWC1 Monoclonal Antibody (OTI1H8), TrueMAB
인간 WWC1 단백질을 인식하는 마우스 단클론 항체로 Western blot에 적합합니다. TrueMAB 형식으로 고순도 친화 크로마토그래피 정제 제품입니다. 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도로 사용 가능합니다. Hippo 신호 경로 연구에 유용합니다.
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Thermo Fisher Scientific WWC1 Monoclonal Antibody (OTI1H8), TrueMAB
Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1H8 |
| Immunogen | Full length human recombinant protein of human WWC1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional round of desalting (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
WWC1 (Protein KIBRA) is a probable regulator of the Hippo/SWH signaling pathway, which plays a key role in tumor suppression by restricting proliferation and promoting apoptosis. WWC1, together with NF2, can synergistically induce phosphorylation of LATS1 and LATS2. It also acts as a transcriptional coactivator of ESR1, essential for DYNLL1-mediated ESR1 transactivation, and functions as a regulator of collagen-stimulated activation of the ERK/MAPK cascade.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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