Thermo Fisher Scientific NBN Monoclonal Antibody (OTI1G8), TrueMAB
Human NBN 단백질을 표적으로 하는 Mouse IgG2b 단클론 항체로, Western blot에 적합. 항체는 Lyophilized 형태이며, PBS buffer에 trehalose 포함. 재구성 후 1 mg/mL 농도, 연구용으로 DNA 손상 복구 관련 단백질 연구에 활용 가능.
- 판매단위
- pk
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1G8 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 183–460 of human NBN produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
The p95 gene (also known as NBS1 or nibrin) is part of the hMre11/hRad50 double-strand break complex.
This complex is implicated in Nijmegen breakage syndrome, an autosomal recessive disorder associated with increased cancer incidence, cell cycle checkpoint defects, and sensitivity to ionizing radiation.
It provides a direct molecular link between double-strand break repair and cell cycle checkpoint functions.
For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.
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