Thermo Fisher Scientific FCER2 Monoclonal Antibody (OTI7C9), TrueMAB
인간 FCER2(CD23) 단백질을 인식하는 Mouse IgG2a 단일클론 항체로, Western blot 및 유세포분석에 사용 가능. 동결건조 형태로 제공되며, PBS 및 trehalose buffer에 저장. 연구용으로 B세포 성장 및 IgE 관련 연구에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Flow Cytometry (Flow)
- Tested Dilution: Assay-Dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7C9 |
| Immunogen | Human recombinant protein fragment (aa 48–321 of human FCER2, produced in insect cells) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
CD23 is a 45 kDa glycoprotein expressed on a subset of peripheral blood and tonsil B cells, and strongly on EBV-transformed B lymphoblasts. It functions as the low-affinity IgE receptor on B cells.
Expression is observed in neoplastic cells from B cell chronic lymphocytic leukemia and certain lymphomas.
Functionally, CD23 is involved in B cell growth, differentiation, and IgE production. The soluble form acts as a potent mitogenic factor.
Diseases associated with CD23 dysfunction include chronic conjunctivitis and chronic lymphocytic leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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