Thermo Fisher Scientific TAFA5 Polyclonal Antibody
TAFA5 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체. 인간, 생쥐, 랫트 반응성. Western blot 검증 완료. 세포 이동 및 골흡수 관련 연구에 적합. 항원 친화 크로마토그래피로 정제된 고순도 제품.
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- PA547702
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Thermo Fisher Scientific TAFA5 Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 0.5 µg/mL
Species Reactivity
- Human
- Mouse
- Rat
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived recombinant human TAFA5/FAM19A5 (Gln26–Ser125) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2607054 |
Product Specific Information
- In direct ELISAs, less than 1% cross-reactivity with recombinant human TAFA1, TAFA2, TAFA3, and TAFA4.
- Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
TAFA5 acts as a chemokine-like protein regulating cell proliferation and migration via GPCRs such as S1PR2 and FPR2.
It stimulates macrophage migration through MAPK3/ERK1 and AKT1 pathways and inhibits osteoclast formation by blocking TNFSF11/RANKL-induced gene expression.
TAFA5 also functions as an adipokine, negatively regulating vascular smooth muscle cell proliferation and migration through GPCR S1PR2 and RHOA signaling, thereby inhibiting injury-induced neointima formation in femoral arteries.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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