Thermo Fisher Scientific H3K79me3 Polyclonal Antibody

Thermo Fisher Scientific H3K79me3 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Store vial at -20°C prior to opening.
• Aliquot contents and freeze at -20°C or below for extended storage.
• Avoid cycles of freezing and thawing.
• Centrifuge if solution is not clear after standing at room temperature.
• Stable for several weeks at 4°C as undiluted liquid.
• Dilute only prior to immediate use.

Anti-Histone H3 [Trimethyl Lys79] reacts with human Histone H3.
BLAST analysis suggests cross-reactivity with human, mouse, and C. elegans.
Predicted to react with rat, chicken, Xenopus, Drosophila, and plant species based on 100% sequence homology.
Cross-reactivity with other sources has not been determined.

Target Information

Histone H3 is a DNA-binding protein found in the chromatin of all eukaryotic cells.
Together with other core histones, it forms the nucleosome structure.
Histones regulate transcription, DNA repair, replication, and chromosomal stability.
The N-terminal tail of histone H3 undergoes post-translational modifications such as methylation, acetylation, and phosphorylation, influencing chromatin structure and gene expression.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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