Thermo Fisher Scientific COX10 Polyclonal Antibody
Thermo Fisher Scientific의 COX10 Polyclonal Antibody는 인간 COX10 단백질을 인식하는 토끼 유래 항체로, Western blot에 적합합니다. 미토콘드리아 복합체 IV 결함 연구에 활용되며, 다양한 종에 예측 반응성을 보입니다. 항원 친화 크로마토그래피로 정제된 고품질 연구용 시약입니다.
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Applications and Tested Dilution
- Western Blot (WB): 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human COX10 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792549 |
Product Specific Information
- Keep as a concentrated solution.
- Predicted reactivity: Mouse (92%), Zebrafish (81%), Xenopus laevis (84%), Pig (93%), Chicken (87%), Rhesus Monkey (97%), Bovine (92%).
- Positive Control: U87-MG, SK-N-SH, IMR-32, SK-N-AS.
- Centrifuge briefly prior to opening the vial.
Target Information
Defects in COX10 are a cause of mitochondrial complex IV deficiency (MT-C4D), also known as cytochrome c oxidase deficiency. This disorder affects the mitochondrial respiratory chain and can manifest as isolated myopathy or severe multisystem disease involving multiple tissues and organs. Clinical features may include hypertrophic cardiomyopathy, hepatomegaly, liver dysfunction, hypotonia, muscle weakness, exercise intolerance, developmental delay, and mental retardation. Some patients may present with Leigh syndrome.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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