Thermo Fisher Scientific Calsequestrin Polyclonal Antibody
Calsequestrin 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. Human, Mouse, Rat에 반응하며 항원 친화성 크로마토그래피로 정제되었습니다. 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
- Western Blot (WB): 1:500–1:3,000
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human Calsequestrin 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.79 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol, 1% BSA |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792548 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Mouse (96%), Rat (96%), Pig (96%), Rabbit (96%), Bovine (94%).
- Positive Control: HepG2, mouse muscle, rat muscle.
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The sarcoplasmic reticulum (SR) maintains intracellular calcium levels in cardiac and skeletal muscle by storing and releasing calcium. Among several SR calcium-binding proteins, Calsequestrin is the most prominent. It sequesters calcium accumulated in the SR during muscle relaxation and is localized to the junctional and corbular regions (terminal cisternae) of the SR. Calsequestrin localizes calcium near the terminal cisternae, from which calcium is released into the cytosol via the ryanodine receptor. This protein is highly acidic with a large capacity and moderate to low affinity for calcium.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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