Thermo Fisher Scientific FGD1 Polyclonal Antibody
인간 FGD1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 최적화되어 있으며 고순도 항원 친화 크로마토그래피로 정제됨. 0.85 mg/mL 농도의 액상 형태로 제공되며, 단기 4°C 보관 및 장기 -20°C 보관 권장.
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Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the C-terminus region of human FGD1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.85 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2792550 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Mouse (98%), Rat (98%), Bovine (100%).
- Positive Control: Target recombinant protein, U87-MG, SK-N-SH, IMR32, SK-N-AS.
- Centrifuge briefly prior to opening the vial.
Target Information
FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It binds specifically to the Rho family GTPase Cdc42Hs and stimulates the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also activates the mitogen-activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation.
FGD1 plays an essential role in embryonic development, and mutations in the FGD1 gene cause Aarskog-Scott syndrome.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information: www.P65Warnings.ca.gov
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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