Thermo Fisher Scientific SNTB2 Polyclonal Antibody
SNTB2 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC(P), ICC/IF에 사용 가능. Human, Mouse, Rat 반응성. Affinity chromatography로 정제된 1 mg/mL 액상 항체로, -20°C 보관. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SNTB2 (Accession Q13425), corresponding to amino acid residues Y203–A253 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900579 |
Product Specific Information
Antibody detects endogenous levels of total SNTB2.
Target Information
Syntrophins are structurally related proteins located at the neuromuscular synapse and play an important role in dystrophin-associated protein (DAP) complex formation.
Three distinct syntrophin isoforms have been identified: alpha 1, beta 1, and beta 2.
Each protein contains a PDZ domain, a syntrophin-unique domain (SU), and three pleckstrin homology domains (PH1a, 1b, and 2).
The PDZ domain mediates binding of syntrophin to nNOS and the DAP complex, facilitating localization of the nicotinic acetylcholine receptor to the cytoskeleton via the (S/T)XV C terminus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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