Thermo Fisher Scientific SORL1 Polyclonal Antibody
SORL1 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot과 Immunocytochemistry에 사용 가능. 인간, 마우스, 랫트 반응성. 합성 펩타이드 면역원 기반으로 제작되었으며, 액상 형태로 -20°C 보관. 연구용 전용 제품.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SORL1 (Accession Q92673), corresponding to amino acid residues V1625–P1675. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900583 |
Product Specific Information
Antibody detects endogenous levels of total SorLA.
Target Information
This gene encodes a mosaic protein that belongs to at least two families: the vacuolar protein sorting 10 domain-containing receptor family, and the low density lipoprotein receptor family.
The encoded protein also contains fibronectin type III repeats and an epidermal growth factor repeat.
The encoded protein is translated as a preproprotein and likely plays roles in endocytosis and sorting.
There may be an association between expression of this locus and Alzheimer’s Disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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