Thermo Fisher Scientific SMARCB1 Polyclonal Antibody
SMARCB1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(P) 실험에 적합합니다. 인체, 생쥐, 랫드 시료에 반응하며, 고순도의 친화 크로마토그래피 정제 항체입니다. PBS와 글리세롤 기반 용액으로 안정적 보관이 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SMARCB1 (Accession Q12824), corresponding to amino acid residues E115–P165 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | –20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2900575 |
Product Specific Information
Antibody detects endogenous levels of total SNF5.
Target Information
The SWI-SNF complex is involved in transcription activation through ATP-dependent nucleosome remodeling. Brm (SNF2α) and Brg-1 (SNF2β) are the ATPase subunits of the mammalian SWI-SNF complex. Brm, Brg-1, Ini1 (SNF5), BAF155 (SRG3), and BAF170 form the functional core of this complex. Addition of Ini1, BAF155, and BAF170 to Brg-1 enhances remodeling activity, while other subunits have regulatory roles. hSNF2L and hSNF2H are homologs of Drosophila ISWI, present in other chromatin remodeling complexes such as NURF.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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