Thermo Fisher Scientific Guanine nucleotide-binding protein alpha-q/GNAQ/G-ALPHA-q Monoclonal Antibody (GNAQ/2434)
GNAQ 단백질을 인식하는 마우스 단클론 항체로, 인간 시료에 반응합니다. ICC/IF, Flow Cytometry, ELISA에 사용 가능하며, 1 mg/mL 농도의 액상 형태입니다. 단백질 A/G로 정제되었으며, PBS(pH 7.4) 버퍼에 보존제로 없이 제공됩니다.
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Thermo Fisher Scientific GNAQ Monoclonal Antibody (GNAQ/2434)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
| ELISA | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GNAQ/2434 |
| Immunogen | Recombinant full-length human GNAQ protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Guanine nucleotide-binding proteins are a family of heterotrimeric proteins that couple cell surface, 7-transmembrane domain receptors to intracellular signaling pathways. Receptor activation catalyzes the exchange of GTP for GDP bound to the inactive G protein alpha subunit, resulting in a conformational change and dissociation of the complex. The G protein alpha and beta-gamma subunits regulate various cellular effectors. Activation is terminated by a GTPase intrinsic to the G-alpha subunit. G-alpha-q is the alpha subunit of one of the heterotrimeric GTP-binding proteins that mediates stimulation of phospholipase C-beta.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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