Thermo Fisher Scientific DCAMKL1 Monoclonal Antibody (6H4)
DCAMKL1 단백질을 인식하는 Mouse IgG1 단클론 항체(6H4). Western blot, ICC/IF, ELISA에 적합. 인간 및 생쥐 반응성. PBS 버퍼에 보존제 없이 제공되며 -20°C에서 보관. 연구용으로만 사용.
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- H00009201-M03
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Thermo Fisher Scientific DCAMKL1 Monoclonal Antibody (6H4)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 0.1 ng/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6H4 |
| Immunogen | DCAMKL1 (NP_004725, approx. 640–729 a.a.) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
QVLEHPWVND DGLPENEHQL SVAGKIKKHF NTGPKPNSTA AGVSVIALDH GFTIKRSGSL DYYQQPGMYW IRPPLLIRRG RFSDEDATRM
Target Information
DCAMKL1 (DCLK1) is a serine/threonine kinase containing two N-terminal doublecortin domains that bind microtubules and regulate their polymerization, a C-terminal serine/threonine protein kinase domain homologous to Ca²⁺/calmodulin-dependent kinase, and a serine/proline-rich domain mediating protein-protein interactions.
DCAMKL1 is a microtubule-associated kinase capable of autophosphorylation and exhibits microtubule-polymerizing activity independent of its kinase function. It plays roles in neuronal migration, retrograde transport, neuronal apoptosis, and neurogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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