Thermo Fisher Scientific ZBED1 Polyclonal Antibody, MaxPab
인간 ZBED1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 검증 완료. 세포 증식 및 DNA 복제 관련 연구에 적합. PBS 버퍼에 보존되며 -20°C에서 보관.
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Thermo Fisher Scientific ZBED1 Polyclonal Antibody, MaxPab
Applications
- Western Blot (WB)
Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | ZBED1 (NP_004720.1, 1–694 a.a) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MENKSLESSQTDLKLVAHPRAKSKVWKYFGFDTNAEGCILQWKKIYCRICMAQIAYSGNTSNLSYHLEKNHPEEFCEFVKSNTEQMREA... (full sequence retained for reference)
Target Information
ZBED1 (also known as DREF) is the human homolog of the Drosophila DREF protein, a transcriptional regulatory factor required for expression of genes involved in DNA replication and cell proliferation. RNAi experiments targeting ZBED1 resulted in inhibition of S phase entry and reduction of histone H1 mRNA in HeLa cells, indicating its role in cell proliferation.
At least 22 ribosomal proteins possess ZBED1 binding sites in their promoters. Immunoprecipitation analyses have shown that ZBED1 self-associates via a carboxyl-terminal hATC domain, which is required for nuclear localization and DNA binding.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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