Thermo Fisher Scientific LRRFIP1 Polyclonal Antibody, MaxPab
LRRFIP1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot에 적합하며 인간 및 생쥐 시료에 반응. 친화 크로마토그래피로 정제된 액상 항체로, PBS(pH 7.4) 용액에 보존제 없이 제공. -20°C에서 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | LRRFIP1 (AAH10662.1, 1 a.a. ~ 105 a.a) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MHVMDLQRDA NRQISDLKFK LAKSEQEITA LEQNVIRLES QVSRYKSAAE NAEKIEDELK AEKRKLQREL RSALDKTEEL EVSNGHLVKR LEKMKANRSA LLSQQ
Target Information
Leucine-rich repeat FLI-I interacting protein 1 (LRRFIP1/FLAP-1) is a MyD88-interacting signal protein that mediates induction or repression of TLR signaling.
Flap-1 directly interacts with β-catenin and activates β-catenin-dependent transcription activity.
It also binds the TNF- -308 promoter polymorphism site, suggesting a role in TNF- production regulation.
FLAP-1, along with LRRFIP2 and FLIIH, coordinates inflammatory responses after infection and may serve as a novel target for controlling TLR-mediated inflammatory and autoimmune diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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