Thermo Fisher Scientific PRMT2 Monoclonal Antibody (OTI1A3), TrueMAB
PRMT2 단백질을 인식하는 Mouse 모노클로날 항체로 Western Blot 및 IHC(Paraffin)에 적합. HEK293T 세포에서 생산된 full-length human recombinant protein을 면역원으로 사용. 고순도 Affinity chromatography 정제, Lyophilized 형태로 제공. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1A3 |
| Immunogen | Full length human recombinant protein of human PRMT2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of about 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
PRMT2 is an arginine methyltransferase that methylates the guanidino nitrogens of arginyl residues in proteins such as STAT3, FBL, and histone H4.
Acts as a coactivator with NCOA2 for androgen receptor (AR)-mediated transactivation and with estrogen for ER-mediated transactivation.
Enhances PGR, PPARG, and RARA-mediated transactivation.
May inhibit NF-kappa-B transcription and promote apoptosis.
Represses E2F1 transcriptional activity in an RB1-dependent manner and may be involved in growth regulation.
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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