Thermo Fisher Scientific PRMT2 Monoclonal Antibody (OTI3A3), TrueMAB
인간 PRMT2 단백질을 인식하는 마우스 단클론 항체로 Western blot, IHC, ICC/IF에 적합. 고순도 친화 크로마토그래피 정제, 동결건조 형태. 연구용으로만 사용 가능하며, 안정적인 PBS 버퍼에 보존됨.
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Thermo Fisher Scientific PRMT2 Monoclonal Antibody (OTI3A3), TrueMAB
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3A3 |
| Immunogen | Full length human recombinant protein of human PRMT2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
PRMT2 is an arginine methyltransferase that methylates guanidino nitrogens of arginyl residues in proteins such as STAT3, FBL, and histone H4.
Acts as a coactivator with NCOA2 for androgen receptor (AR)-mediated transactivation and with estrogen for estrogen receptor (ER)-mediated transactivation.
Enhances PGR, PPARG, and RARA-mediated transactivation, may inhibit NF-kappa-B transcription, promote apoptosis, repress E2F1 transcriptional activity (RB1-dependent), and be involved in growth regulation.
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(해당 항원 이미지: CF503643_PRMT2_P55345-1_House_mouse.svg / CF503643_PRMT2_P55345-1_House_mouse_PDP.jpeg)
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