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Thermo Fisher Scientific Phospho-TLK1 (Ser743) Polyclonal Antibody
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TLK1 단백질의 Ser743 인산화 부위를 인식하는 Rabbit Polyclonal Antibody. 인간, 마우스, 랫트 반응성. Western blot에 적합하며 고순도(>95%) 항체. 연구용으로 DNA 손상 반응 및 크로마틴 조립 연구에 활용 가능.
- 판매단위
- pk
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마지막 업데이트 2025. 07. 29. 오후 04:01
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Thermo Fisher Scientific PA537340 Phospho-TLK1 (Ser743) Polyclonal Antibody 100 ul pk판매 단위 pk ·
재고 확인 필요
693,100원VAT 포함 762,410원
Thermo Fisher Scientific · Thermo Fisher Scientific Phospho-TLK1 (Ser743) Polyclonal Antibody
Thermo Fisher Scientific Phospho-TLK1 (Ser743) Polyclonal Antibody
Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phosphopeptide derived from human TLK1 around the phosphorylation site of Serine 743 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2554016 |
Product Specific Information
- Detects endogenous TLK1 protein at a molecular weight of approximately 86 kDa.
- Purity >95% by SDS-PAGE.
Target Information
TLK1 (Tousled-like kinase 1) is a nuclear serine/threonine kinase involved in chromatin assembly regulation.
Originally described in Arabidopsis, TLK1 is a novel target of the DNA damage checkpoint, rapidly inactivated upon exposure to ionizing radiation.
Its suppression after DNA double-strand breaks, replication blockade, or UV irradiation requires ATM, NBS, and CHK1.
These kinases play key roles in maintaining genomic stability during DNA replication and repair.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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