Thermo Fisher Scientific Bcl-X (Apoptosis Marker) Recombinant Rabbit Monoclonal Antibody (BCL2L1/4509R)
인간 BCL-X 단백질을 표적으로 하는 재조합 토끼 단일클론 항체로, 세포사멸(apoptosis) 연구용 마커로 사용됩니다. IHC(PFA 고정) 실험에 적합하며, 고순도 Protein A/G 정제 방식으로 제조되었습니다. PBS 버퍼에 보관하며 4°C에서 안정적입니다.
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Thermo Fisher Scientific Bcl-X (Apoptosis Marker) Recombinant Rabbit Monoclonal Antibody (BCL2L1/4509R)
Applications
- Immunohistochemistry (PFA fixed) (IHC (PFA))
Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | BCL2L1/4509R |
| Immunogen | Recombinant fragment (around aa1–100) of human BCL2L1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by the BCL-X gene belongs to the BCL-2 protein family. Members of this family form hetero- or homodimers and act as anti- or pro-apoptotic regulators involved in diverse cellular activities. These proteins are located at the outer mitochondrial membrane and regulate the VDAC channel opening, which affects mitochondrial membrane potential and controls reactive oxygen species production and cytochrome C release—key steps in apoptosis induction.
Alternative splicing produces multiple transcript variants encoding two isoforms: the longer isoform acts as an apoptotic inhibitor, while the shorter isoform functions as an apoptotic activator.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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