Thermo Fisher Scientific BCL2-like 2 (BCL2L2)/BCL-W Monoclonal Antibody (PCRP-BCL2L2-1A4)
BCL2L2/BCL-W 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, Human 시료에 반응합니다. ICC/IF, Flow Cytometry, Immunoprecipitation 등에 사용 가능하며, Protein A/G로 정제된 액상 형태입니다. 4°C 보관, 동결 금지.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
| Immunoprecipitation (IP) | 1–2 µg |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PCRP-BCL2L2-1A4 |
| Immunogen | Recombinant human full-length BCL2L2 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Using a PCR-based strategy, an additional protein with life-promoting activity, designated Bcl-w, has been identified. The protein is highly conserved between mouse and human and is encoded by a gene located near the TCRα gene on chromosome 14. Bcl-w is expressed in myeloid cell lines but not in T and B lymphocytes, and can be found in a wide range of tissues.
An alternative splicing event in exon 4 results in two transcripts:
- Bcl-w: encodes a protein of 193 amino acids
- Bcl-w/rox: encodes a protein of 333 amino acids
The rox portion of Bcl-w/rox shows approximately 66% amino acid sequence identity with the Drosophila rox2 protein. However, the Bcl-w/rox transcript may be expressed at very low levels.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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