Thermo Fisher Scientific IGF2BP3 Monoclonal Antibody (C2-E4)
IGF2BP3 단백질을 인식하는 Thermo Fisher Scientific의 C2-E4 단클론 항체. Western blot, IHC, ICC/IF, Flow cytometry 등 다양한 응용 가능. 인간, 마우스, 랫트 반응성. 고순도 Protein A 정제, 장기 안정적 보관 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C2-E4 |
| Immunogen | Recombinant protein within Human IMP-3 (aa 352–579) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS (pH 7.4) with 50% Glycerol, 0.2% BSA |
| Contains | 0.05% Sodium Azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C and avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2802485 |
Target Information
Insulin-like growth factor-II messenger RNA (mRNA)-binding protein-3 (IMP-3), also known as K homology domain-containing protein overexpressed in cancer (KOC) and L523S, is a member of the insulin-like growth factor-II mRNA-binding protein family. It is expressed during embryogenesis and in certain malignancies. IMP-3 is found in malignant melanoma but not in benign nevi, even when dysplastic features are present. It is expressed more frequently in melanomas than in Spitz nevi and more in metastatic melanomas than in thin melanomas. IMP-3 may play a role in melanoma progression and the regulation of tumor behavior.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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