Thermo Fisher Scientific RXRG/NR2B3 (Transcription Factor) Monoclonal Antibody (PCRP-RXRG-5H4)
인간 RXRG 단백질을 인식하는 단클론 항체로, ICC/IF, Flow Cytometry, ELISA, IP 등 다양한 응용에 사용 가능. 단백질 농도 1 mg/mL, PBS(pH 7.4) 용액 형태로 제공. 단백질 정제는 Protein A/G 방식이며, 보존제 무첨가. -20°C에서 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
| ELISA | Assay-dependent |
| Immunoprecipitation (IP) | 1–2 µg/100–500 µg total protein |
| Peptide Array | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PCRP-RXRG-5H4 |
| Immunogen | Recombinant full-length human RXRG protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Predicted to react in Mouse, Rat, and Chick.
Target Information
Retinoic Acid (RA), the active metabolite of vitamin A, plays a crucial role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005).
The Retinoid X Receptors (RXRs) family — RXR alpha, beta, and gamma — preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with another family of RA receptors.
RAs have been suggested to play a potential therapeutic role in cervical cancer (Abu et al., 2005). They are also known to influence neuronal development, with evidence indicating that retinoid signaling regulates synaptic plasticity and behaviors associated with learning and memory (Lane and Bailey, 2005).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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