Thermo Fisher Scientific ING3 Polyclonal Antibody
Human, Mouse, Rat 반응성을 가진 Rabbit Polyclonal ING3 항체로, Western blot에 적합합니다. 항원 친화 크로마토그래피로 정제된 고순도 항체이며, PBS/glycerol 버퍼에 보존됩니다. 세포 성장 억제 및 apoptosis 관련 연구에 유용합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human ING3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720561 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis.
This protein contains a PHD-finger motif common in chromatin remodeling proteins.
It can activate p53 trans-activated promoters, including p21/waf1 and bax.
Overexpression inhibits cell growth and induces apoptosis.
Allelic loss and reduced expression have been detected in head and neck cancers.
Two alternatively spliced transcript variants encoding different isoforms have been observed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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