
Thermo Fisher Scientific MARCKSL1 Polyclonal Antibody
Thermo Fisher Scientific의 MARCKSL1 Polyclonal Antibody는 인간, 마우스, 랫트에서 반응하며 Western blot에 적합합니다. 항원 친화 크로마토그래피로 정제된 고순도 항체로, 액상 형태이며 장기 보관 시 -20°C에서 안정적으로 유지됩니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human MARCKSL1 (UniProt ID: P49006-1, Antigen range: 1–195, length: 195) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720874 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
MARCKS (Myristoylated alanine-rich protein kinase C substrate), also designated 80K or 80K-L, is a 332 amino acid protein localized to the plasma membrane and functions as a major substrate for protein kinase C (PKC).
MARCKSL1 (MARCKS-like protein 1), also known as MacMARCKS, MLP, MRP, or F52, is a 195 amino acid protein and a major substrate for PKC. It is expressed in various tissues, with highest levels in testis and uterus. MARCKSL1 participates in membrane-cytoskeletal signaling events such as secretion, migration, phagocytosis, and cell adhesion. It also regulates Integrin activation and Integrin-dependent signal transduction pathways, especially those involved in macrophage spreading.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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