Thermo Fisher Scientific Phospho-4EBP1 (Ser65) Monoclonal Antibody (T.730.9)
Phospho-4EBP1 (Ser65) 단일클론 항체로, Western Blot 및 Immunoprecipitation 검증 완료. 인간, 생쥐, 영장류 반응성. Rabbit IgG 형식이며, 비결합형 액상 제품. 고순도 친화 크로마토그래피 정제, -20°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
- View 1 publication
Immunoprecipitation (IP)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | T.730.9 |
| Immunogen | Synthetic phosphopeptide corresponding to residues surrounding pSer65 of mouse 4E-BP1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 156.5 µg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | <0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_10978119 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
This gene encodes one member of a family of translation repressor proteins.
The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5′ end of mRNAs.
Interaction with eIF4E inhibits complex assembly and represses translation.
Phosphorylation occurs in response to signals such as UV irradiation and insulin signaling, causing dissociation from eIF4E and activation of mRNA translation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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