Thermo Fisher Scientific LKB1 Monoclonal Antibody (B.593.0)
LKB1 단백질을 인식하는 rabbit monoclonal 항체로, Western blot과 Immunoprecipitation에 적합합니다. Human 및 비인간 영장류 시료에 반응하며, 고순도의 affinity chromatography로 정제되었습니다. 액상 형태로 -20°C에서 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunoprecipitation (IP) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | B.593.0 |
| Immunogen | Synthetic peptide corresponding to the sequence of human LKB1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 45 µg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | <0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_10979314 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
LKB1 (also known as STK11 - Serine/threonine-protein kinase STK11) is a tumor suppressor and a member of the serine/threonine kinase family. It physically associates with p53 and regulates specific p53-dependent apoptosis pathways. LKB1 is localized in both the cytoplasm and nucleus and translocates to mitochondria during apoptosis. It functions as a master upstream protein kinase, regulating AMPK-related kinases as well as AMPK. Mutations in the LKB1 gene are associated with Peutz-Jeghers syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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