Thermo Fisher Scientific Beclin 1 Polyclonal Antibody
Beclin 1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot 및 IHC에 적합하며, Drosophila Beclin 1의 350-400 aa 합성 펩타이드로 면역 생성. 자가포식 연구 및 PI3K 복합체 관련 연구에 활용 가능.
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Thermo Fisher Scientific Beclin 1 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous (PubMed) | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Fruit fly |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide from aa region 350–400 of Drosophila Beclin 1 conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 150 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity: Beclin-1.
Target Information
Beclin 1 plays a central role in autophagy as a core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate.
Different PI3K complex forms are believed to play roles in multiple membrane trafficking pathways:
- PI3KC3-C1: involved in initiation of autophagosomes
- PI3KC3-C2: involved in maturation of autophagosomes and endocytosis
Beclin 1 also contributes to antiviral host defense mechanisms.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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