Thermo Fisher Scientific TLR10 Polyclonal Antibody
TLR10 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. WB, IHC, ICC/IF에 사용 가능하며 인간 시료에 반응. 1 mg/mL 농도의 액상 형태로 제공되며 PBS 버퍼 및 sodium azide 포함. 병원체 인식 및 선천면역 연구에 적합.
- 카탈로그번호
- PA520054
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 0.5–1 µg/mL
Immunohistochemistry (IHC)
- Tested Dilution: Not specified
Immunocytochemistry (ICC/IF)
- Tested Dilution: 2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A peptide corresponding to 14 amino acids near the middle of human TLR10 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Ion-exchange chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11154271 |
Product Specific Information
Despite its predicted molecular weight of ~90 kDa, TLR10 is observed at ~75 kDa in immunoblot assays.
A suggested positive control is human lymph node tissue lysate.
PA5-20054 can be used with blocking peptide PEP-0173.
Target Information
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity.
TLRs are highly conserved from Drosophila to humans and share structural and functional similarities.
They recognize pathogen-associated molecular patterns (PAMPs) expressed on infectious agents and mediate cytokine production necessary for effective immunity.
TLR10 is most highly expressed in lymphoid tissues such as spleen, lymph node, thymus, and tonsil.
Its exact function is not yet known. Multiple alternatively spliced transcript variants encoding the same protein have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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