Thermo Fisher Scientific PTX3 Monoclonal Antibody (MNB1)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:50

-

Flow Cytometry (Flow)

1:50

-

Functional Assay (Functional)

1:50

-

Inhibition Assays (IA)

1:50

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rat / IgG2b

Class

Monoclonal

Type

Antibody

Clone

MNB1

Immunogen

Human recombinant PTX3 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PTX3,uniProtId:P26022-1,ncbiNodeId:9606,antigenRange:1-381,antigenLength:381,antigenImageFileName:MA5-49096_PTX3_P26022-1_Rat.svg,antigenImageFileNamePDP:MA5-49096_PTX3_P26022-1_Rat_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

100 µg/mL

Purification

Protein G

Storage buffer

PBS with 0.1% BSA

Contains

no preservative

Storage conditions

4° C

Shipping conditions

Wet ice

RRID

AB_3091072

Target Information

Pentraxins are a protein superfamily that is characterized by a cyclic multimeric structure. Ptx3, also known as tumor necrosis factor-stimulated gene sequence-14 (TSG14), is a secreted pattern-recognition receptor that has a non-redundant role in resistance to selected microbial agents. Ptx3 belongs to the family of long pentraxins, which have C-terminal pentraxin domains and novel amino-terminal domains. Ptx3 binds selected pathogens, including Aspergillus fumigatus, Pseudomonas aeruginosa and Salmonella typhimurium. It is synthesized in IgA glomerulonephritis and activates mesangial cells. Secretion of Ptx3 in adipose cells can be induced by TNF. Ptx3 is also involved in amplification of inflammatory reactions and regulation of innate immunity. The human PTX3 gene maps to chromosome 3q25.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.