Thermo Fisher Scientific PR3 Monoclonal Antibody (PR3G-2), FITC
인간 PR3 단백질을 인식하는 마우스 모노클로날 항체(PR3G-2)로, FITC 형광 표지되어 있습니다. Western blot, Flow cytometry, Functional 및 Inhibition assay에 사용 가능하며, 단백질 G로 정제된 액상 형태입니다. 4°C 암소 보관 및 연구용으로만 사용됩니다.
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Thermo Fisher Scientific PR3 Monoclonal Antibody (PR3G-2), FITC
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:50 |
| Flow Cytometry (Flow) | 1:50 |
| Functional Assay | 1:50 |
| Inhibition Assays (IA) | 1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PR3G-2 |
| Immunogen | Monoclonal antibody PR3G-2 reacts with human proteinase 3 (PR3), a 30 kDa protein |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 100 µg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Wet ice |
| RRID | AB_3093270 |
Additional Formats
- Unconjugated: MA1-40218
- Request custom conjugation available
Product Specific Information
The monoclonal antibody PR3G-2 was produced by immunization of mice with a crude granule extract.
Target Information
Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) (PubMed:3198760, PubMed:2033050, PubMed:28240246).
By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration (PubMed:23202369).
May play a role in neutrophil transendothelial migration, probably when associated with CD177 (PubMed:22266279). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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