Thermo Fisher Scientific Complement C3G Monoclonal Antibody (9)

Applications

Tested Dilution

Publications

Immunoprecipitation (IP)

1:50

-

Inhibition Assays (IA)

1:50

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rat / IgG1

Class

Monoclonal

Type

Antibody

Clone

9

Immunogen

The monoclonal antibody 9 reacts with a neoantigen on iC3, iC3b, C3dg and C3g if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Complement C3g,uniProtId:P01024-1,ncbiNodeId:9606,antigenRange:1-1663,antigenLength:1663,antigenImageFileName:MA5-49099_Complement_C3g_P01024-1_Rat.svg,antigenImageFileNamePDP:MA5-49099_Complement_C3g_P01024-1_Rat_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

100 µg/mL

Purification

Protein G

Storage buffer

PBS with 0.1% BSA

Contains

0.02% sodium azide

Storage conditions

4° C

Shipping conditions

Wet ice

RRID

AB_3091124

Product Specific Information

The monoclonal antibody 9 recognizes iC3b, C3dg and C3g in plasma. The monoclonal antibody does not recognize C3 or C3b.

Target Information

The complement factor C3 consists of an alpha and a beta chain. C3 is a central factor in the complement cascade. It is central to the alternative pathway that leads to the C3 convertase C3bBb. The classical mannose binding lectin activation pathway leads to the C3 convertase C4b2a. These convertases cleave C3 resulting in C3a and C3b. Further degradation leads to the formation of the alpha chain products C3d, C3g and C3c. C3 is an acute phase protein that is produced by a wide range of tissues, including renal epithelial cells and hepatocytes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.