Thermo Fisher Scientific IDH1 Polyclonal Antibody
Thermo Fisher Scientific의 IDH1 Polyclonal Antibody는 인간 IDH1 (mutant R132H)에 특이적으로 반응하는 항체로, Western blot 및 Immunoprecipitation에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 4°C에서 보관합니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Assay-dependent
Immunoprecipitation (IP)
- 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1 to 50 of human Isocitrate Dehydrogenase 1 (IDH1, mutant R132H) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/Tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Predicted to react with Bovine and Orangutan based on 100% sequence identity
Target Information
Isocitrate dehydrogenases such as IDH1 catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one utilizing NAD(+) and the other NADP(+) as electron acceptors. Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent (mitochondrial matrix localized) and two NADP(+)-dependent (one mitochondrial, one cytosolic).
The NADP(+)-dependent cytosolic enzyme encoded by this gene contains a PTS-1 peroxisomal targeting signal sequence and plays a key role in cytoplasmic NADPH production. This antibody is specific for IDH1 (mutant R132H).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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