Thermo Fisher Scientific C1QA Polyclonal Antibody
Western blot, ICC/IF, ELISA에 사용 가능한 C1QA 폴리클로날 항체. 인간 및 생쥐 반응성. 항원 친화 크로마토그래피로 정제된 액상 제품. 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | View 2 publications |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | - |
| ELISA | - | View 1 publication |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 13–225 of Human Complement C1qA |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.18 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2547062 |
Product Specific Information
- Recommended positive controls: human plasma, mouse spleen
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
Target Information
C1q is a sub-component of complement C1 and associates with complement components C1r and C1s, which are required for the progression of the proteolytic complement cascade.
Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis.
C1q is composed of 18 polypeptide chains (six A-, six B-, and six C-chains).
Each chain contains a collagen-like region near the N-terminus and a C-terminal globular region.
The A-, B-, and C-chains are arranged in the order A–C–B on chromosome 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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