Thermo Fisher Scientific Synaptophysin Monoclonal Antibody (SP11)
Synaptophysin 단백질 검출용 Rabbit Monoclonal Antibody (Clone SP11). Western blot, IHC, ICC 등 다양한 응용에 적합. 인간, 마우스, 랫트 시료 반응성. 비결합형 액상 포맷으로 제공되며 장기 보관 시 -20°C 권장.
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Thermo Fisher Scientific Synaptophysin Monoclonal Antibody (SP11)
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:200 | View 8 publications |
| Immunohistochemistry (IHC) | - | View 39 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 | View 3 publications |
| Immunocytochemistry (ICC/IF) | 1:250 | View 7 publications |
| Miscellaneous PubMed (Misc) | - | View 4 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | SP11 |
| Immunogen | Synthetic peptide of human synaptophysin (aa 250–313) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Tissue culture supernatant/TBS, pH 7.5, with 1% BSA |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C (avoid freeze/thaw cycles) |
| Shipping Conditions | Wet ice |
| RRID | AB_10983675 |
Product Specific Information
MA5-14532 targets Synaptophysin in IHC (P) and WB applications and shows reactivity with human samples.
The immunogen is a synthetic peptide of human synaptophysin.
Target Information
Synaptophysin is a calcium-binding integral membrane glycoprotein present in presynaptic vesicles of neurons.
It has four transmembrane domains and forms a complex with dynamin at high calcium concentrations, suggesting involvement in synaptic vesicle endocytosis.
Synaptophysin plays a role in short- and long-term synaptic plasticity and is widely used as a marker for nerve terminals and neuroendocrine tumor differentiation.
Mutations in the gene can lead to X-linked mental retardation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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