Thermo Fisher Scientific Synaptophysin Monoclonal Antibody (SP11)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:200

View 8 publications 8 publications

Immunohistochemistry (IHC)

-

View 39 publications 39 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200

View 3 publications 3 publications

Immunocytochemistry (ICC/IF)

1:250

View 7 publications 7 publications

Miscellaneous PubMed (Misc)

-

View 4 publications 4 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Monoclonal

Type

Antibody

Clone

SP11

Immunogen

A synthetic peptide of human synaptophysin (aa 250-313). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Synaptophysin,uniProtId:P08247-1,ncbiNodeId:9606,antigenRange:250-313,antigenLength:313,antigenImageFileName:MA5-14532_Synaptophysin_P08247-1_Rabbit.svg,antigenImageFileNamePDP:MA5-14532_Synaptophysin_P08247-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Storage buffer

tissue culture supernatant/TBS, pH 7.5, with 1% BSA

Contains

0.1% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_10983675

Product Specific Information

MA5-14532 targets Synaptophysin in IHC (P) and WB applications and shows reactivity with Human samples.

The MA5-14532 immunogen is a synthetic peptide of human synaptophysin.

Target Information

Synaptophysin is a calcium-binding and integral membrane glycoprotein present in presynaptic vesicles in almost all neurons. Synaptophysin has four transmembrane domains and it forms a complex with dynamin at high calcium concentrations suggesting an involvement in synaptic vesicle endocytosis. It is also involved in the regulation of short-term and long-term synaptic plasticity. Synaptophysin is currently the most widely used marker for nerve terminals and for differentiating neuroendocrine tumors. Mutations in the gene can result in mental retardation, X-linked 96.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.