Thermo Fisher Scientific Kir6.2 (KCNJ11) Polyclonal Antibody
Kir6.2 (KCNJ11) 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, IHC 및 ICC/IF에 사용 가능. 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제되어 고순도 확보. 연구용으로만 사용.
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Thermo Fisher Scientific Kir6.2 (KCNJ11) Polyclonal Antibody
Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
- Immunocytochemistry (ICC/IF): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 188–243 of Human KCNJ11 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719059 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
This receptor is controlled by G proteins. Inward rectifier potassium channels preferentially allow potassium to flow into the cell rather than out. Their voltage dependence is regulated by extracellular potassium concentration; as external potassium increases, the channel opening voltage shifts positively. Inward rectification is mainly due to blockage of outward current by internal magnesium and can be inhibited by extracellular barium.
KCNJ11 is a subunit of ATP-sensitive potassium channels (KATP), forming cardiac and smooth muscle-type KATP channels with ABCC9. KCNJ11 forms the channel pore, while ABCC9 is required for activation and regulation.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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