Thermo Fisher Scientific MCHR2 Polyclonal Antibody
MCHR2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, IHC 및 ICC/IF에 사용 가능. 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제되어 고순도 확보. 연구용으로만 사용 가능.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 300–340 of Human MCH-2R |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719057 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. Purity is >95% (by SDS-PAGE).
Target Information
Melanin-concentrating hormone (MCH) is a 19 amino acid cyclic neuropeptide mainly expressed in the hypothalamus. MCH modulates feeding behavior, aggression, anxiety, arousal, and reproductive function in mammals by controlling luteinizing hormone (LH) release.
The melanin-concentrating hormone receptor (MCHR, also designated SLC-1) is a glycosylated G-protein coupled receptor migrating between 45–50 kDa on SDS-PAGE. MCHR mediates MCH effects through Gai and/or Gaq signaling and is expressed in regions such as the cerebral cortex, amygdala, thalamus, and hypothalamus.
MCH and MCHR also stimulate leptin expression and secretion in adipocytes, suggesting potential roles in obesity modulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-75329_MCHR2_Q969V1-1_Rabbit.svg)
(이미지 파일명: PA5-75329_MCHR2_Q969V1-1_Rabbit_PDP.jpeg)
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