Thermo Fisher Scientific CD18 Recombinant Rabbit Monoclonal Antibody (ARC0400)
Thermo Fisher Scientific의 CD18 재조합 토끼 단클론 항체(ARC0400)는 인간 CD18 단백질을 인식하며, Western blot과 ELISA에 적합합니다. 고순도 친화 크로마토그래피 정제, 액상 형태, -20°C 보관 안정성. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- MA535201
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CD18 Recombinant Rabbit Monoclonal Antibody (ARC0400)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC0400 |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 50–150 of human CD18 (P05107) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.2 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849105 |
Product Specific Information
Immunogen sequence:
NFTGPGDPDS IRCDTRPQLL MRGCAADDIM DPTSLAETQE DHNGGQKQLS PQKVTLYLRP GQAAAFNVTF RRAKGYPIDL YYLMDLSYSM LDDLRNVKKL G
Target Information
CD18 integrin beta 2 subunit is a 90 kDa type I transmembrane protein expressed on all leucocytes. CD18 can combine with integrin molecules CD11a–c to form heterodimers at the cell surface, which participate in cell adhesion and signaling.
CD18 forms heterodimers with four types of CD11 molecules to constitute leukocyte (β2) integrins:
- αLβ2 (CD11a/CD18, LFA-1)
- αMβ2 (CD11b/CD18, Mac-1, CR3)
- αXβ2 (CD11c/CD18)
- αDβ2 (CD11d/CD18)
These integrins are essential for proper leukocyte migration and intercellular contact. Absence of CD18 results in leukocyte adhesion deficiency-1 (LAD1), and reduced expression may lead to psoriasiform skin disease. CD18 is also a target of Mannheimia haemolytica leukotoxin, mediating cytolysis. Two transcript variants encoding CD18 have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.