Thermo Fisher Scientific ALK Monoclonal Antibody (OTI1D4), TrueMAB
인간 ALK 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot에 적합합니다. HEK293T 세포에서 발현된 full-length ALK 단백질을 면역원으로 사용하였으며, 1 mg/mL 농도의 액상 형태로 제공됩니다. -20°C에서 보관하며 반복 동결·해동은 피해야 합니다.
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Applications
- Western Blot (WB): 1:2,000 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1D4 |
| Immunogen | Full length human recombinant protein of human ALK produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Anaplastic Lymphoma Receptor Tyrosine Kinase (ALK) belongs to the insulin receptor superfamily and is vital for brain development. Mutations, rearrangements, and amplifications in the ALK gene have been found in tumors such as anaplastic large cell lymphoma, neuroblastoma, and non-small cell lung cancer. Chromosomal rearrangement is the most common genetic alteration, creating a fusion gene consisting of the ALK gene and the nucleophosmin (NPM) gene. The NPM-ALK fusion gene product is oncogenic. ALK is a receptor protein-tyrosine kinase with a transmembrane and extracellular domain, showing the greatest sequence similarity to LTK. It plays an important role in brain development and neuronal function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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