Thermo Fisher Scientific CXCR6 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A peptide corresponding to amino acids 319 to 338 of human BONZO if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CXCR6,uniProtId:O00574-1,ncbiNodeId:9606,antigenRange:319-338,antigenLength:342,antigenImageFileName:PA5-19888_CXCR6_O00574-1_Rabbit.svg,antigenImageFileNamePDP:PA5-19888_CXCR6_O00574-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Ion-exchange chromatography

Storage buffer

PBS

Contains

0.02% sodium azide

Storage conditions

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_11157259

Product Specific Information

A suggested positive control is SW1353 cell lysate.

PA5-19888 can be used with blocking peptide PEP-0016.

Target Information

CD186, also known as CXCR6, is a G protein-coupled chemokine receptor reported to be one of the cellular receptors of HIV and SIV. CD186 is expressed by NKT cells, various subtypes of T cells with activated and memory phenotypes, and some plasma cells. It has been reported that mouse liver NK cells, but not naïve or splenic NK cells, express CD186. The ligand of CD186, CXCL16, is expressed by macrophages, dendritic cells and liver endothelial cells. Being highly expressed on NKT cells, CD186 is often used as a proxy marker of this cell subset.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.