Thermo Fisher Scientific ITIH2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

Assay-dependent

-

Immunocytochemistry (ICC/IF)

2 µg/mL

-

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide corresponding to residues E A N N L G L L D P N. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ITIH2,uniProtId:P19823-1,ncbiNodeId:9606,antigenRange:401-411,antigenLength:946,antigenImageFileName:PA1-1756_ITIH2_P19823-1_Rabbit.svg,antigenImageFileNamePDP:PA1-1756_ITIH2_P19823-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2171386

Product Specific Information

PA1-1756 detects HC2 from human and mouse samples.

PA1-1756 has been successfully used in immunohistochemical staining of paraffin embedded tissue sections.

The PA1-1756 immunogen is a synthetic peptide corresponding to residues E A N N L G L L D P N. This immunizing peptide (PEP-302) is available for neutralization and control experiments.

Target Information

The inter-alpha-trypsin inhibitors (ITI) are a family of structurally related plasma serine protease inhibitors involved in extracellular matrix stabilization and in prevention of tumor metastasis. The ITI family contains multiple proteins made up of a light chain (see MIM 176870) and a variable number of heavy chains (Salier et al., 1987 [PubMed 2446322]; Himmelfarb et al., 2004 [PubMed 14744536]). ITI-HC2 may act as a carrier of hyaluronan in serum or as a binding protein between hyaluronan and other matrix protein, including those on cell surfaces in tissues to regulate the localization, synthesis and degradation of hyaluronan which are essential to cells undergoing biological processes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.