Thermo Fisher Scientific ADAMTS9 Polyclonal Antibody
Thermo Fisher Scientific의 ADAMTS9 Polyclonal Antibody는 인간 ADAMTS9 단백질을 인식하는 토끼 IgG 항체입니다. Western blot 및 면역세포화학(ICC/IF)에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS/BSA 완충액에 보관되며 연구용으로만 사용됩니다.
- 카탈로그번호
- PA11760
- 판매단위
- pk
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.5 µg/mL | View 1 publication |
| Immunocytochemistry (ICC/IF) | 2 µg/mL | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues C F D G K H F N I N G L L P N of human ADAMTS9 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 1 mg/mL BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2222488 |
Product Specific Information
- PA1-1760 detects ADAMTS9 from human samples.
- Successfully used in Western blotting procedures.
- Immunogen: synthetic peptide corresponding to residues C F D G K H F N I N G L L P N of human ADAMTS9.
- Also referred to as JSCFDG.
Target Information
ADAMTS proteases are secreted enzymes containing a prometalloprotease domain of the reprolysin type. These proteases function in processing of procollagens and von Willebrand factor, as well as catabolism of aggrecan, versican, and brevican. They play crucial roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis, and cell migration.
The immunizing peptide sequence is 100% conserved between human, mouse, and rat.
ADAMTS9 is a member of the ADAMs family of proteinases with Thrombospondin motifs and shares 54% overall identity with ADAMTS20. It contains a GON-like domain at the carboxyterminal end, similar to the GON-1 protein in C. elegans, which is associated with gonadal development.
ADAMTS9 is expressed in ovary, testis, heart, placenta, lung, skeletal tissue, and pancreas, suggesting functions beyond reproductive development. Like ADAMTS20, ADAMTS9 has 15 thrombospondin-like domains.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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