Thermo Fisher Scientific Desmoglein 2 (DSG2) Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 635-935 of human DSG2 (NP_001934.2). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Desmoglein 2 (DSG2),uniProtId:Q14126-1,ncbiNodeId:9606,antigenRange:635-935,antigenLength:1118,antigenImageFileName:PA5-121232_Desmoglein_2_DSG2_Q14126-1_Rabbit.svg,antigenImageFileNamePDP:PA5-121232_Desmoglein_2_DSG2_Q14126-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

4.96 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2914804

Product Specific Information

Positive test controls include: HepG2, HeLa, SW620, DU145, K-562. The target is usually found in the following locations: Cell junction, Cell membrane, Single-pass type I membrane protein, desmosome.

Immunogen sequence: CHCGKGAKGF TPIPGTIEML HPWNNEGAPP EDKVVPSFLP VDQGGSLVGR NGVGGMAKEA TMKGSSSASI VKGQHEMSEM DGRWEEHRSL LSGRATQFTG ATGAIMTTET TKTARATGAS RDMAGAQAAA VALNEEFLRN YFTDKAASYT EEDENHTAKD CLLVYSQEET ESLNASIGCC SFIEGELDDR FLDDLGLKFK TLAEVCLGQK IDINKEIEQR QKPATETSMN TASHSLCEQT MVNSENTYSS GSSFPVPKSL QEANAEKVTQ EIVTERSVSS RQAQKVATPL PDPMASRNVI A

Target Information

Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.