Thermo Fisher Scientific Desmoglein 2 (DSG2) Polyclonal Antibody
Desmoglein 2(DSG2)에 특이적인 Rabbit Polyclonal Antibody로, Human, Mouse, Rat 시료에 반응합니다. Western blot 및 ELISA에 적합하며, 세포 접합부 단백질 연구에 활용됩니다. 고순도 Affinity 정제 및 안정한 PBS/glycerol 포뮬레이션으로 제공됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 635–935 of human DSG2 (NP_001934.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 4.96 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914804 |
Product Specific Information
Positive test controls include: HepG2, HeLa, SW620, DU145, K-562.
The target is usually found in the following locations: Cell junction, Cell membrane, Single-pass type I membrane protein, desmosome.
Immunogen sequence:
CHCGKGAKGF TPIPGTIEML HPWNNEGAPP EDKVVPSFLP VDQGGSLVGR NGVGGMAKEA TMKGSSSASI VKGQHEMSEM DGRWEEHRSL LSGRATQFTG ATGAIMTTET TKTARATGAS RDMAGAQAAA VALNEEFLRN YFTDKAASYT EEDENHTAKD CLLVYSQEET ESLNASIGCC SFIEGELDDR FLDDLGLKFK TLAEVCLGQK IDINKEIEQR QKPATETSMN TASHSLCEQT MVNSENTYSS GSSFPVPKSL QEANAEKVTQ EIVTERSVSS RQAQKVATPL PDPMASRNVI A
Target Information
Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types.
Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily.
These desmoglein gene family members are located in a cluster on chromosome 18.
This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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