Thermo Fisher Scientific IMPDH1 Polyclonal Antibody
Thermo Fisher Scientific의 IMPDH1 Polyclonal Antibody는 인간, 마우스, 랫트 시료에 반응하며 WB, ICC/IF, ELISA에 적합합니다. 세포 성장 조절 효소 IMPDH1을 검출하며, 고순도 Affinity Chromatography 정제 및 안정적인 PBS/glycerol 저장 조건을 제공합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 434–563 of human IMPDH1 (NP_899066.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 3.18 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914805 |
Product Specific Information
Positive test controls include NIH/3T3, 293T, BT-474.
Target localization: Cytoplasm, Nucleus.
Immunogen sequence:
MMGSLLAATT EAPGEYFFSD GVRLKKYRGM GSLDAMEKSS SSQKRYFSEG DKVKIAQGVS GSIQDKGSIQ KFVPYLIAGI QHGCQDIGAR SLSVLRSMMY SGELKFEKRT MSAQIEGGVH GLHSYEKRLY
Target Information
The protein encoded by this gene acts as a homotetramer to regulate cell growth. It catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP), the rate-limiting step in de novo synthesis of guanine nucleotides.
Defects in this gene cause retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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