Thermo Fisher Scientific HMGN1 Polyclonal Antibody
HMGN1 단백질을 인식하는 Thermo Fisher Scientific의 고순도 폴리클로날 항체입니다. Western blot에 적합하며 인간, 마우스, 랫트 시료에서 반응합니다. 항원 친화 크로마토그래피로 정제되어 SDS-PAGE 기준 95% 이상 순도입니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific HMGN1 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:1,000
Publications: - [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues in Human HMGN1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719315 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is >95% as determined by SDS-PAGE.
Target Information
The high-mobility group (HMG) proteins 14 and 17 are abundant chromosomal proteins that bind to nucleosomes and enhance transcription. These proteins act as architectural elements, altering chromatin structure and promoting transcription from chromatin templates. HMG-14/17 modify the nucleosomal organization of the 30 nm chromatin fiber and mediate unfolding of higher-order chromatin structures, facilitating access to underlying DNA sequences. Clustering of HMG proteins and linker histone subtypes into distinct domains may create structural and functional heterogeneity along the chromatin fiber. Additionally, HMG-14 and HMG-17 are constitutive components of mouse oocyte and embryonic chromatin, linking chromatin structure to normal embryonic development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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