Thermo Fisher Scientific NBS1 Polyclonal Antibody
Human 및 Mouse 시료에 반응하는 Rabbit Polyclonal NBS1 항체. Western blot 및 IHC에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 형태. PBS 버퍼에 0.02% sodium azide 함유. 냉장 보관(2–8°C), 장기 보관 시 -20°C.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunohistochemistry (IHC) | 2.5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 15 amino acid synthetic peptide near the carboxy terminus of human NIBRIN |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551736 |
Product Specific Information
- A suggested positive control is mouse lung tissue lysate.
- PA5-34384 can be used with blocking peptide PEP-1427.
Target Information
The p95 gene (identical to NBS1 and nibrin) is a member of the hMre11/hRad50 double-strand break complex.
This protein complex has been implicated in Nijmegen breakage syndrome, an autosomal recessive disorder marked by increased cancer incidence, cell cycle checkpoint deficits, and ionizing radiation sensitivity.
This reveals a direct molecular link between double-strand break repair and cell cycle checkpoint functions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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