
Thermo Fisher Scientific Phospho-SMC3 (Ser1067) Polyclonal Antibody
Phospho-SMC3 (Ser1067) 폴리클로날 항체로, 인간·마우스·랫트 시료에서 사용 가능. Western blot 및 IHC(파라핀) 실험에 적합. SMC3 단백질의 Ser1067 인산화 형태를 특이적으로 검출. 고순도 정제 및 안정적 PBS/glycerol 저장용액 제공.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
- Publications: 참고 문헌 보기
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
- Publications: 참고 문헌 보기
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SMC3 (Accession Q9UQE7), corresponding to amino acid residues around phosphorylated Ser1067 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2903270 |
Product Specific Information
Antibody detects endogenous levels of Bamacan only when phosphorylated at Ser1067.
Target Information
This gene belongs to the SMC3 subfamily of SMC proteins. The encoded protein occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein.
The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation.
Post-translational modification of the encoded protein by the addition of chondroitin sulfate chains gives rise to the secreted proteoglycan bamacan, an abundant basement membrane protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-118770_SMC3_Q9UQE7-1_Rabbit.svg)
(이미지: PA5-118770_SMC3_Q9UQE7-1_Rabbit_PDP.jpeg)
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